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Cefaclor Generic (Ceclor) from Canada

Cefaclor generic is a widespread antibiotic that fights with infections and inflammations of different natures. Assigned orally, possible side effects include diarrhea and skin rashes.

Distribution

The medicine is available in most Canadian pharmacies, and if necessary, you can order Cefaclor online. But before placing an order, you must make sure that the site you have chosen is safe and that the products presented are original. The price of Cefaclor depends on the dosage and quantity of tablets. The cost varies from $144.99 to $214.99 per 90 tablets. Don’t forget to consult your doctor before starting the Cefaclor treatment course. It should be noted that this drug could be sold only by prescription.

Cefaclor description and use

Cefaclor is popular antibiotic that is often used in Canada and all over the world. This medicine has a wide spectrum of use and is effective against different types of bacteria. Diseases of the upper and respiratory tracts of the lungs, including pneumonia, urinary tract infections, infections of the skin and soft tissues, pyelonephritis, and rhinitis are examples of infectious and inflammatory conditions that result in bacteria sensitive to cefaclor.

This medicine is well absorbed from the gastrointestinal tract and has a fast-acting mechanism of action. Cefaclor is rapidly distributed throughout the body and reaches therapeutic concentrations in most tissues and fluids. The maximum concentration of active components in blood plasma is reached after 0.5–1 h.

Cefaclor dosage depends on body weight and type of disease. The most precise treatment could be prescribed only by a doctor individually, taking into account the severity of the course and localization of the infection, the sensitivity of the pathogen, the age of the patient, and the dosage form used. But, according to the recommendations, the following dosing regimen should be used:

  • Children: This medication is contraindicated in children under the age of 1 month. Inside, the maximum daily dose is 40 mg / kg.
  • Adults: Inside, 250–500 mg 3 times a day. Highest daily dose: 4 g. The highest single dose: 500 mg.

If you’ve missed the necessary dose, please take the pill as soon as possible, but never use the extra dose. Missing 1 dose will not affect the efficiency of the treatment. If you feel any adverse symptoms while using Cefaclor, you should immediately stop taking medicine and contact your therapist.

Side effects and contradictions

Side effect

Usually, side effects are not very common during the Cefaclor treatment course. Sometimes the following conditions could happen: Allergic reactions. If patient has intolerance to cefaclor, or to any other components of the medication, the treatment course should be changed. The continuation of treatment with Cefaclor, could lead to serious health problems.

Among others pretty common side effects, the headache and dizziness could be observed. But it’s important to mention, that Cefaclor doesn’t affect the ability of driving vehicles.

Rhinitis, sneezing, cough and other symptoms related to the respiratory system are very rare. But some patients note that long-term use of the drug can cause such symptoms.

If a woman suffers from a violation of the microflora of the intimate area, this symptom such as vaginitis may occur.

Nausea, vomiting, diarrhea, cholestatic jaundice, pseudomembranous colitis, increased activity of hepatic transaminases, hepatitis are also in the list of side effects, but they are faced only in 5% of the patients.

Contraindications for use

Individual intolerance to β-lactam antibiotics: penicillins and cephalosporins, children under 1 month of age. It should also be taken with caution in cases of electrolyte or fluid imbalance, a history of bronchial asthma, severe liver damage, or malabsorption syndrome.

With caution

Use with caution in chronic renal failure. It is possible to use Cefaclor in children of the appropriate age categories strictly according to the indications, int the recommended doses and dosage forms. It is necessary to strictly follow the instructions for cefaclor preparations on contraindications for use in children of different ages of specific dosage forms.

In the case of overdose, increased side effects could be observed. Overdose is often manifested by nausea, vomiting, diarrhea, and epigastric pain. Cefaclor has low toxicity. Even high doses administered over a long period of time are well tolerated. Only in cases of exceeding the dose, which is more than a daily dose, at least 5 times, should activated charcoal be administered, vomiting be induced, or gastric lavage be performed. There is no specific antidote There are no sufficient studies on the effectiveness of forced diuresis, peritoneal dialysis or hemodialysis, and hemoperfusion via activated charcoal that could recommend their use. Supportive and symptomatic treatment is recommended.

Drug interaction

The use of Cefaclor with other drugs should be permitted by your doctor. Don’t forget to tell about all the medication and other supplies that you use regularly.

  • The simultaneous use of probenecid slows down the excretion of cefaclor by reducing the tubular secretion of the latter.
  • With the simultaneous use of cefaclor, the nephrotoxicity of aminoglycosides, polymyxins, and phenylbutazone increases (mutually).
  • With simultaneous use, the antibacterial effect of cefaclor is increased by aminoglycosides, metronidazole, polymyxins, and rifampicin, and weakened by chloramphenicol and tetracyclines.
  • With the simultaneous use of antacids containing magnesium or aluminum hydroxide, the degree of absorption of cefaclor is slowed down. Histamine H2 receptor blockers (cimetidine, ranitidine, nizatidine, roxatidine, and famotidine) do not affect the rate and extent of absorption.
  • With simultaneous use of tubular secretion blockers, the kidneys delay the excretion of cefaclor.